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The 11th edition of the Manuale-Prontuario di Diagnostica e Terapia Medica introduces several new topics that broaden the range of conditions useful for refining the diagnostic skills of internists. In addition to a comprehensive new chapter on COVID-19 and its complications, new sections address pulmonary hypertension, abdominal and thoracic aortic aneurysms, mixed connective tissue disease, fibromyalgia and other clinical conditions.
Some chapters have been substantially revised, such as the one on diabetes mellitus, updated with numerous new drugs that significantly expand the available treatment options, although they can sometimes be challenging to implement in general practice. Several appendices, including the dietetics section, have also been extensively updated with new concepts and dietary recommendations for various diseases, thanks to the contribution of dietitian Dr. Caterina Civale.
The volume offers a diagnostic and therapeutic approach to major internal medicine disorders that is both rigorous and practical, grounded in the real needs of physicians. It aims to support accurate diagnosis by combining clinical examination with reasonably accessible instrumental methods, while avoiding purely theoretical techniques that are difficult to apply and preventing underestimation of serious diseases that may present with apparently minor symptoms.
Therapeutic recommendations exclude non-validated or anti-scientific treatments that still circulate in some settings or online, and instead rely firmly on the scientific method and international guidelines, focusing solely on effective, evidence-based therapies. This strict selection of validated treatments remains one of the core strengths of the work.
Hospital-based therapies are also described in sufficient detail to make the book a useful reference for clinicians working in hospital settings.
Overall, it remains a quick-reference tool and, at the same time, a rigorous update for the daily practice of general practitioners and internists.