Diabete e Malattie Cardiovascolari

520-page volume with numerous illustrations and tables. Hardcover with color-printed and laminated cover.

This text provides an exhaustive and updated review of all clinical aspects of cardiovascular disease in diabetics, delving into the relationships between diabetes, atherosclerosis, macro and microangiopathy, and the clinical consequences at the heart, kidney, eye, and brain levels. The text also explores the pathogenetic aspects of vascular damage in diabetics. Diabetes is a disease of growing social-health importance, both due to its high prevalence and the long-term complications it causes.

This statement is even more significant when related to the progressive aging of the population, in terms of disability and comorbidities, especially for cardiovascular, neurological, renal, and ocular complications. In this text, the authors address diabetic pathology in relation to pathogenetic mechanisms and risk factors (hypertension, dyslipidemia, thrombophilia), providing the most up-to-date data on epidemiology, etiopathogenesis, diagnostic evaluation, and therapy of micro and macroangiopathy.

The text examines in detail diabetic retinopathy, nephropathy, neuropathy, and microangiopathy. The chapters are extremely detailed and exhaustive, with numerous updated bibliographic references. The text “Diabetes and Cardiovascular Diseases” therefore provides trainees, general practitioners, and specialists with the most up-to-date knowledge necessary for a full understanding of diabetic disease and for adopting the most current and rational therapy for each patient.

The text is divided into 4 sections. The first section, which addresses the pathophysiology of diabetic disease, illustrates the characteristics of plurimetabolic syndrome, the effect of insulin on the cardiovascular system, the effect of diabetes on endothelial function, typical vascular alterations in the prediabetic state, the mechanism of damage from advanced glycation end products, the relationship between diabetes and the renin-angiotensin system, diabetes and vascular complications, diabetes and fibrinolysis, nitric oxide production, hypertension, dyslipidemia, thrombosis, and atherosclerosis. This section also includes a chapter on animal models.

The second section is dedicated to the heart, particularly ischemic heart disease, heart failure, and the pre and post-operative management of diabetic patients. The third section explores the relationship between diabetes and peripheral circulation, in terms of epidemiology, diagnosis, and therapy. Finally, the fourth section addresses the relationship between diabetes and microangiopathy, in the renal, ocular, and nervous vascular beds. The final chapter provides an exhaustive analysis of diabetic foot.

The text is accompanied by a complete analytical index and clear and comprehensive illustrations and tables.